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For brain tumor treatment in particular, the systems are required to have a capability of both BBB crossing and tumor targeting

10.1016/j.neulet.2020.135268 76 IzumiY.SawadaH.YamamotoN.KumeT.KatsukiH.ShimohamaS.et al

Table 2 presents the PubMed search related to targeting the transferrin receptor, LDL receptor, glucose transporter and GSH transporter for brain targeting agent development